Three are programmes our scientists run for you, and one puts the technologies in your own team’s hands.
From sequencing data to a ranked, evidence linked list of targets.
From a target to a nominated list of candidate molecules.
From sequencing reads to a candidate molecule, under one scope.
The technologies in your team’s hands, on your own targets and data.
You have sequencing data, but no target.
You have a target, but no candidate molecules.
You have data and a disease question, and want molecules at the end.
You have a computational team and want to run the work yourselves.
Your team needs the skills before the software.
AcademyWorkshops, internships, the Advanced Diploma and research support.
You are not sure yet.
Whichever programme you commission, you receive results you can defend and the record behind them.
Targets or candidates in order, each with the evidence behind its position.
Suitable for a grant, a filing or a partner discussion.
Every parameter set, engine version and log behind the work that produced the results.
Generated molecules narrowed to four candidates by a ten-stage cascade, all inside one session.
The full case studyAround 100,000 de novo molecules shortlisted to fourteen, with the top five checked by molecular dynamics, MM-GBSA and DFT.
Read the paperCandidate modulators of a fungal cell wall target, nominated from the same cascade.
Read the paperThe technologies were built for small molecule discovery, but the filters, endpoints and reporting change with the field. These are the sectors we work in today.
Lead discovery and optimisation against your own targets, with the evidence trail that a partner, a regulator or a diligence process will ask to see.
Hands-on access to the technologies, with manuscript support when the work is ready to publish.
Capacity for computational work delivered under your own reporting, with parameter records your clients can audit.
Crop protection targets, with property filters and toxicity endpoints tuned to the sector.
Crystal structure prediction and solid form work through SilicoCSP, alongside density functional theory for electronic structure.
Programmes in infectious and neglected disease, as in the campaigns above.
No programme starts without a written scope. These steps apply to the three programmes, and a technology licence follows a shorter version of the same path.
One conversation about what you have and what you need. No charge and no obligation.
Scope, deliverables, milestones, timeline and cost, in writing, before any work begins.
Targets and data transferred, technology access provisioned, and a named scientific contact assigned to the programme.
Interim reports at agreed points, so direction can change while there is still budget and time to change it.
Everything listed under “What every delivery contains” is handed over together, and your team can open every job record and rerun any step, with or without us.
The questions a legal or security team will ask, answered before the scoping call rather than after it.
Anything you share stays confidential. We are happy to sign a non disclosure agreement before you send us anything sensitive.
For the programmes we run, the outputs are yours. Data handling, intellectual property and access controls are set per engagement in the written scope.
Where your data sits is part of the same written terms, whichever product you choose.
A scoping call establishes whether there is a problem worth working on together. A computational scientist will discuss how our technologies apply to your programme, which engagement model fits, and whether we are the right partner for the work.
